Docetaxel suppressed cell proliferation through Smad3/HIF-1α-mediated glycolysis in prostate cancer cells

Docetaxel suppressed cell proliferation through Smad3/HIF-1α-mediated glycolysis in prostate cancer cells

Abstract Background Tumor glycolysis is a critical event for tumor progression. Docetaxel is widely used as a first-line drug for chemotherapy and shown to have a survival advantage. However, the role of docetaxel in tumor glycolysis remained poorly understood. Methods The effect of Docetaxel in tum...

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Bibliographic Details
Main Authors: Junming Peng, Zhijun He, Yeqing Yuan, Jing Xie, Yu Zhou, Baochun Guo, Jinan Guo
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Cell Communication and Signaling
Subjects:
Docetaxel
Tumor glycolysis
Smad3
Cell proliferation
Prostate cancer
Online Access:https://doi.org/10.1186/s12964-022-00950-z

Internet

https://doi.org/10.1186/s12964-022-00950-z

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