Siderocalin/Lcn2/NGAL/24p3 does not drive apoptosis through gentisic acid mediated iron withdrawal in hematopoietic cell lines.

Siderocalin/Lcn2/NGAL/24p3 does not drive apoptosis through gentisic acid mediated iron withdrawal in hematopoietic cell lines.

Siderocalin (also lipocalin 2, NGAL or 24p3) binds iron as complexes with specific siderophores, which are low molecular weight, ferric ion-specific chelators. In innate immunity, siderocalin slows the growth of infecting bacteria by sequestering bacterial ferric siderophores. Siderocalin also binds...

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Bibliographic Details
Main Authors: Colin Correnti, Vera Richardson, Allyson K Sia, Ashok D Bandaranayake, Mario Ruiz, Yohan Suryo Rahmanto, Žaklina Kovačević, Matthew C Clifton, Margaret A Holmes, Brett K Kaiser, Jonathan Barasch, Kenneth N Raymond, Des R Richardson, Roland K Strong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3424236?pdf=render

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http://europepmc.org/articles/PMC3424236?pdf=render

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