Genome-wide analysis of genetic predisposition to Alzheimer’s disease and related sex disparities

Abstract Background Alzheimer’s disease (AD) is the most common cause of dementia in the elderly and the sixth leading cause of death in the United States. AD is mainly considered a complex disorder with polygenic inheritance. Despite discovering many susceptibility loci, a major proportion of AD ge...

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Bibliographic Details
Main Authors: Alireza Nazarian, Anatoliy I. Yashin, Alexander M. Kulminski
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Alzheimer’s Research & Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13195-018-0458-8