Pd<sub>2</sub>Spermine Complex Shows Cancer Selectivity and Efficacy to Inhibit Growth of Triple-Negative Breast Tumors in Mice

Pd<sub>2</sub>Spermine Complex Shows Cancer Selectivity and Efficacy to Inhibit Growth of Triple-Negative Breast Tumors in Mice

Pd<sub>2</sub>Spm is a dinuclear palladium(II)-spermine chelate with promising anticancer properties against triple-negative breast cancer (TNBC), a breast carcinoma subset with poor prognosis and limited treatment options. The present study evaluated the in vitro and in vivo anticancer...

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Bibliographic Details
Main Authors: Martin Vojtek, Salomé Gonçalves-Monteiro, Patrícia Šeminská, Katarína Valová, Loreto Bellón, Patrícia Dias-Pereira, Franklim Marques, Maria P. M. Marques, Ana L. M. Batista de Carvalho, Helder Mota-Filipe, Isabel M. P. L. V. O. Ferreira, Carmen Diniz
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Biomedicines
Subjects:
Pd(II)-based drugs
cisplatin
metal complexes
triple-negative breast cancer
in vivo
xenografts
Online Access:https://www.mdpi.com/2227-9059/10/2/210

Internet

https://www.mdpi.com/2227-9059/10/2/210

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