Inhibiting Type VI Secretion System Activity with a Biomimetic Peptide Designed To Target the Baseplate Wedge Complex

Inhibiting Type VI Secretion System Activity with a Biomimetic Peptide Designed To Target the Baseplate Wedge Complex

ABSTRACT Human health is threatened by bacterial infections that are increasingly resistant to multiple drugs. A recently emerged strategy consists of disarming pathogenic bacteria by targeting and blocking their virulence factors. The type VI secretion system (T6SS) is a widespread secretion nanoma...

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Bibliographic Details
Main Authors: Y. Cherrak, I. Filella-Merce, V. Schmidt, D. Byrne, V. Sgoluppi, R. Chaiaheloudjou, S. Betzi, X. Morelli, M. Nilges, R. Pellarin, E. Durand
Format: Article
Language:English
Published: American Society for Microbiology 2021-08-01
Series:mBio
Subjects:
bacterial secretion system
type VI secretion system
T6SS
bioinformatic
biomimetic peptide
protein-protein interface
Online Access:https://journals.asm.org/doi/10.1128/mBio.01348-21

Internet

https://journals.asm.org/doi/10.1128/mBio.01348-21

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