Synthesis and Biological Activity of Piperidinothiosemicarbazones Derived from Aminoazinecarbonitriles

Synthesis and Biological Activity of Piperidinothiosemicarbazones Derived from Aminoazinecarbonitriles

To investigate how structural modifications affect tuberculostatic potency, we synthesized seven new piperidinothiosemicrabazone derivatives <b>8</b>–<b>14</b>, in which three of them had a pyrazine ring replacing the pyridine ring. Derivatives <b>8</b>–<b>9...

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Bibliographic Details
Main Authors: Dagmara Ziembicka, Katarzyna Gobis, Małgorzata Szczesio, Ewa Augustynowicz-Kopeć, Agnieszka Głogowska, Izabela Korona-Głowniak, Krzysztof Bojanowski
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Pharmaceuticals
Subjects:
pyridine
pyrazine
thiosemicarbazone
synthesis
tuberculostatic activity
antimicrobial activity
Online Access:https://www.mdpi.com/1424-8247/16/9/1267

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https://www.mdpi.com/1424-8247/16/9/1267

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