Monocarboxylate Transporter 4 Is a Therapeutic Target in Non-small Cell Lung Cancer with Aerobic Glycolysis Preference

Monocarboxylate Transporter 4 Is a Therapeutic Target in Non-small Cell Lung Cancer with Aerobic Glycolysis Preference

Targeting metabolic reprogramming is an emerging strategy in cancer therapy. However, clinical attempts to target metabolic reprogramming have been proved to be challenging, with metabolic heterogeneity of cancer being one of many reasons that causes treatment failure. Here, we stratified non-small...

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Bibliographic Details
Main Authors: Ting-Chun Kuo, Kuo-Yen Huang, Shuenn-Chen Yang, Sean Wu, Wei-Chia Chung, Yih-Leong Chang, Tse-Ming Hong, Shu-Ping Wang, Hsuan-Yu Chen, Tzu-Hung Hsiao, Pan-Chyr Yang
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Molecular Therapy: Oncolytics
Subjects:
NSCLC
cancer metabolism
metabolic heterogeneity
aerobic glycolysis
MCT4
Sp1
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770520300917

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http://www.sciencedirect.com/science/article/pii/S2372770520300917

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