Preclinical evaluation of oncolytic vaccinia virus for therapy of canine soft tissue sarcoma.

Preclinical evaluation of oncolytic vaccinia virus for therapy of canine soft tissue sarcoma.

Virotherapy using oncolytic vaccinia virus (VACV) strains is one promising new strategy for canine cancer therapy. In this study we describe the establishment of an in vivo model of canine soft tissue sarcoma (CSTS) using the new isolated cell line STSA-1 and the analysis of the virus-mediated oncol...

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Main Authors: Ivaylo Gentschev, Marion Adelfinger, Rafael Josupeit, Stephan Rudolph, Klaas Ehrig, Ulrike Donat, Stephanie Weibel, Nanhai G Chen, Yong A Yu, Qian Zhang, Martin Heisig, Douglas Thamm, Jochen Stritzker, Amy Macneill, Aladar A Szalay
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3352892?pdf=render

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http://europepmc.org/articles/PMC3352892?pdf=render

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