Hypocretin‐1/Hypocretin Receptor 1 Regulates Neuroplasticity and Cognitive Function through Hippocampal Lactate Homeostasis in Depressed Model

Abstract Cognitive dysfunction is not only a common symptom of major depressive disorder, but also a more common residual symptom after antidepressant treatment and a risk factor for chronic and recurrent disease. The disruption of hypocretin regulation is known to be associated with depression, how...

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Bibliographic Details
Main Authors: Bing Chen, Kangyu Jin, Jingyi Dong, Shangping Cheng, Lingzhuo Kong, Shaohua Hu, Zuobing Chen, Jing Lu
Format: Article
Language:English
Published: Wiley 2024-10-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.202405354