Prognostic value, immune signature and molecular mechanisms of the APOBEC family members APOBEC1, APOBEC3A, APOBEC3G and APOBEC3H in pancreatic adenocarcinoma

Prognostic value, immune signature and molecular mechanisms of the APOBEC family members APOBEC1, APOBEC3A, APOBEC3G and APOBEC3H in pancreatic adenocarcinoma

Background: Increasing evidence supports that the APOBEC family is associated with development of a variety of cancers. However, the function of APOBEC1/3A/3G/3H in pancreatic adenocarcinoma (PAAD) is still unclear.Methods: Comprehensive bioinformatic analysis using R (version 3.6.3), TISIDB, Metasc...

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Bibliographic Details
Main Authors: Yunjie Duan, Yongxing Du, Zongting Gu, Xiaohao Zheng, Chengfeng Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Molecular Biosciences
Subjects:
pancreatic adenocarcinoma
APOBEC family
biomarkers
prognosis
immune infiltration
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.1036287/full

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https://www.frontiersin.org/articles/10.3389/fmolb.2022.1036287/full

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