ZBP1 Drives IAV-Induced NLRP3 Inflammasome Activation and Lytic Cell Death, PANoptosis, Independent of the Necroptosis Executioner MLKL

ZBP1 Drives IAV-Induced NLRP3 Inflammasome Activation and Lytic Cell Death, PANoptosis, Independent of the Necroptosis Executioner MLKL

Influenza A virus (IAV) continues to pose a significant global health threat, causing severe respiratory infections that result in substantial annual morbidity and mortality. Recent research highlights the pivotal role of innate immunity, cell death, and inflammation in exacerbating the severity of...

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Bibliographic Details
Main Authors: R. K. Subbarao Malireddi, Bhesh Raj Sharma, Ratnakar R. Bynigeri, Yaqiu Wang, Jianlin Lu, Thirumala-Devi Kanneganti
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Viruses
Subjects:
IAV
cell death
PANoptosis
necroptosis
inflammasome
MLKL
Online Access:https://www.mdpi.com/1999-4915/15/11/2141

Internet

https://www.mdpi.com/1999-4915/15/11/2141

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