Impact of pre-existing MSP1<sub>42</sub>-allele specific immunity on potency of an erythrocytic <it>Plasmodium falciparum</it> vaccine

<p>Abstract</p> <p>Background</p> <p>MSP1 is the major surface protein on merozoites and a prime candidate for a blood stage malaria vaccine. Preclinical and seroepidemiological studies have implicated antibodies to MSP1 in protection against blood stage parasitaemia an...

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Bibliographic Details
Main Authors: Bergmann-Leitner Elke S, Duncan Elizabeth H, Mease Ryan M, Angov Evelina
Format: Article
Language:English
Published: BMC 2012-09-01
Series:Malaria Journal
Subjects:
Online Access:http://www.malariajournal.com/content/11/1/315