Associations of FGF21 and GDF15 with mitochondrial dysfunction in children living with perinatally-acquired HIV: A cross-sectional evaluation of pediatric AIDS clinical trials group 219/219C.

Associations of FGF21 and GDF15 with mitochondrial dysfunction in children living with perinatally-acquired HIV: A cross-sectional evaluation of pediatric AIDS clinical trials group 219/219C.

<h4>Background</h4>In persons living with HIV, mitochondrial disease (MD) is difficult to diagnose, as clinical signs are non-specific with inconsistent patterns. Fibroblast growth factor 21 (FGF21) and growth differentiation factor 15 (GDF15) are mitokines elevated in MD patients withou...

Full description

Bibliographic Details
Main Authors: Greg S Gojanovich, Denise L Jacobson, Carly Broadwell, Brad Karalius, Brian Kirmse, Mitchell E Geffner, Jennifer Jao, Russell B Van Dyke, Elizabeth J McFarland, Margarita Silio, Marilyn Crain, Mariana Gerschenson, Pediatric HIV/AIDS Cohort Study
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0261563

Internet

https://doi.org/10.1371/journal.pone.0261563

Similar Items