Generation of dorsoventral human spinal cord organoids via functionalizing composite scaffold for drug testing

Summary: The spinal cord possesses highly complex, finely organized cytoarchitecture guided by two dorsoventral morphogenic organizing centers. Thus, generation of human spinal cord tissue in vitro is challenging. Here, we demonstrated a novel method for generation of human dorsoventral spinal cord...

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Bibliographic Details
Main Authors: Weiwei Xue, Bo Li, Huihui Liu, Yujie Xiao, Lei Ren, Huijuan Li, Zhicheng Shao
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422202171X