Glutamine metabolism regulates endothelial to hematopoietic transition and hematopoietic lineage specification
Abstract During hematopoietic development, definitive hematopoietic cells are derived from hemogenic endothelial (HE) cells through a process known as endothelial to hematopoietic transition (EHT). During EHT, transitioning cells proliferate and undergo progressive changes in gene expression culmina...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-09-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-97194-7 |