Optical Coherence Tomography-Derived Changes in Plaque Structural Stress Over the Cardiac Cycle: A New Method for Plaque Biomechanical Assessment

Introduction: Cyclic plaque structural stress has been hypothesized as a mechanism for plaque fatigue and eventually plaque rupture. A novel approach to derive cyclic plaque stress in vivo from optical coherence tomography (OCT) is hereby developed.Materials and Methods: All intermediate lesions fro...

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Main Authors: Jiayue Huang, Fan Yang, Juan Luis Gutiérrez-Chico, Tianxiao Xu, Jigang Wu, Liang Wang, Rui Lv, Yan Lai, Xuebo Liu, Yoshinobu Onuma, Dalin Tang, Patrick W. Serruys, William Wijns, Shengxian Tu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Cardiovascular Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.715995/full