CopA3 Peptide Prevents Ultraviolet-Induced Inhibition of Type-I Procollagen and Induction of Matrix Metalloproteinase-1 in Human Skin Fibroblasts

CopA3 Peptide Prevents Ultraviolet-Induced Inhibition of Type-I Procollagen and Induction of Matrix Metalloproteinase-1 in Human Skin Fibroblasts

Ultraviolet (UV) exposure is well-known to induce premature aging, which is mediated by matrix metalloproteinase-1 (MMP-1) activity. A 9-mer peptide, CopA3 (CopA3) was synthesized from a natural peptide, coprisin, which is isolated from the dung beetle Copris tripartitus. As part of our continuing s...

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Bibliographic Details
Main Authors: Dong-Hee Kim, Han-Hyuk Kim, Hyeon-Jeong Kim, Hyun-Gug Jung, Jae-Myo Yu, Eun-Su Lee, Yong-Hun Cho, Dong-In Kim, Bong-Jeun An
Format: Article
Language:English
Published: MDPI AG 2014-05-01
Series:Molecules
Subjects:
Copris tripartitus
CopA3
ultraviolet
matrix metalloproteinase-1
CCD-986sk cells
Online Access:http://www.mdpi.com/1420-3049/19/5/6407

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http://www.mdpi.com/1420-3049/19/5/6407

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