Cystine–glutamate antiporter deletion accelerates motor recovery and improves histological outcomes following spinal cord injury in mice

Cystine–glutamate antiporter deletion accelerates motor recovery and improves histological outcomes following spinal cord injury in mice

Abstract xCT is the specific subunit of System xc-, an antiporter importing cystine while releasing glutamate. Although xCT expression has been found in the spinal cord, its expression and role after spinal cord injury (SCI) remain unknown. The aim of this study was to characterize the role of xCT o...

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Bibliographic Details
Main Authors: Lindsay Sprimont, Pauline Janssen, Kathleen De Swert, Mathias Van Bulck, Ilse Rooman, Jacques Gilloteaux, Ann Massie, Charles Nicaise
Format: Article
Language:English
Published: Nature Portfolio 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91698-y

Internet

https://doi.org/10.1038/s41598-021-91698-y

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