A thermostable type I-B CRISPR-Cas system for orthogonal and multiplexed genetic engineering

A thermostable type I-B CRISPR-Cas system for orthogonal and multiplexed genetic engineering

Abstract Thermophilic cell factories have remarkably broad potential for industrial applications, but are limited by a lack of genetic manipulation tools and recalcitrance to transformation. Here, we identify a thermophilic type I-B CRISPR-Cas system from Parageobacillus thermoglucosidasius and find...

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Bibliographic Details
Main Authors: Zhiheng Yang, Zilong Li, Bixiao Li, Ruihong Bu, Gao-Yi Tan, Zhengduo Wang, Hao Yan, Zhenguo Xin, Guojian Zhang, Ming Li, Hua Xiang, Lixin Zhang, Weishan Wang
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-41973-5

Internet

https://doi.org/10.1038/s41467-023-41973-5

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