Tertiary lymphoid structures in pancreatic cancer: a new target for immunotherapy

Pancreatic cancer (PC) is extremely malignant and shows limited response to available immunotherapies due to the hypoxic and immunosuppressive nature of its tumor microenvironment (TME). The aggregation of immune cells (B cells, T cells, dendritic cells, etc.), which is induced in various chronic in...

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Bibliographic Details
Main Authors: Xinlei Zou, Canghai Guan, Jianjun Gao, Wujiang Shi, Yunfu Cui, Xiangyu Zhong
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1222719/full