Functional Regulation of KATP Channels and Mutant Insight Into Clinical Therapeutic Strategies in Cardiovascular Diseases

Functional Regulation of KATP Channels and Mutant Insight Into Clinical Therapeutic Strategies in Cardiovascular Diseases

ATP-sensitive potassium channels (KATP channels) play pivotal roles in excitable cells and link cellular metabolism with membrane excitability. The action potential converts electricity into dynamics by ion channel-mediated ion exchange to generate systole, involved in every heartbeat. Activation of...

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Bibliographic Details
Main Authors: Zhicheng Wang, Weikang Bian, Yufeng Yan, Dai-Min Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Pharmacology
Subjects:
KATP channels
mitoKATP channels
myocardial ischemia
channelopathy
small active molecules
mutation
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.868401/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.868401/full

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