Fast and accurate Ab Initio Protein structure prediction using deep learning potentials.

Despite the immense progress recently witnessed in protein structure prediction, the modeling accuracy for proteins that lack sequence and/or structure homologs remains to be improved. We developed an open-source program, DeepFold, which integrates spatial restraints predicted by multi-task deep res...

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Bibliographic Details
Main Authors: Robin Pearce, Yang Li, Gilbert S Omenn, Yang Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-09-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1010539