Synaptosome microRNAs regulate synapse functions in Alzheimer’s disease

Abstract MicroRNAs (miRNAs) are found in nerve terminals, synaptic vesicles, and synaptosomes, but it is unclear whether synaptic and cytosolic miRNA populations differ in Alzheimer’s disease (AD) or if synaptosomal miRNAs affect AD synapse activity. To address these questions, we generated synaptos...

Full description

Bibliographic Details
Main Authors: Subodh Kumar, Erika Orlov, Prashanth Gowda, Chhanda Bose, Russell H. Swerdlow, Debomoy K. Lahiri, P. Hemachandra Reddy
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:npj Genomic Medicine
Online Access:https://doi.org/10.1038/s41525-022-00319-8