Physicochemical Profile of Antiandrogen Drug Bicalutamide: Solubility, Distribution, Permeability

The pharmacologically relevant physicochemical properties of the antiandrogen drug bicalutamide (BCL) have been determined for the first time. Solubility in aqueous solution, 1-octanol, n-hexane, and ethanol was measured by the shake flask method in the temperature range of 293.15–313.15 K. The comp...

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Bibliographic Details
Main Authors: Tatyana V. Volkova, Olga R. Simonova, German L. Perlovich
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/14/3/674