DDCI-01, a novel long acting phospdiesterase-5 inhibitor, attenuated monocrotaline-induced pulmonary hypertension in rats

Pulmonary arterial hypertension is a progressive, malignant heart disease, characterized by pulmonary arteriole remodeling and increased pulmonary vascular resistance, which eventually leads to right heart failure. This study sought to evaluate the effects of a novel long-acting phospdiesterase-5 in...

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Bibliographic Details
Main Authors: Ailing Li, Zhongkai Zhu, Yangke He, Qian Dong, Dianyong Tang, Zhongzhu Chen, Wei Huang
Format: Article
Language:English
Published: Wiley 2020-11-01
Series:Pulmonary Circulation
Online Access:https://doi.org/10.1177/2045894020939842