Toward a Multivalent Synthetic Oligosaccharide-Based Conjugate Vaccine against <i>Shigella</i>: State-of-the-Art for a Monovalent Prototype and Challenges

Toward a Multivalent Synthetic Oligosaccharide-Based Conjugate Vaccine against <i>Shigella</i>: State-of-the-Art for a Monovalent Prototype and Challenges

This review focuses on the molecular glycovaccine concept, a promising option to develop a <i>Shigella</i> glycoconjugate vaccine. Subsequent to original developments involving, as main vaccine component, the detoxified <i>Shigella</i> lipopolysaccharide randomly conjugated a...

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Bibliographic Details
Main Authors: Armelle Phalipon, Laurence A. Mulard
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Vaccines
Subjects:
carbohydrates
conjugate vaccines
glycoconjugates
O-antigens
<i>Shigella</i>
synthetic glycans
Online Access:https://www.mdpi.com/2076-393X/10/3/403

Internet

https://www.mdpi.com/2076-393X/10/3/403

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