Exercise attenuates neurological deficits by stimulating a critical HSP70/NF-κB/IL-6/synapsin I axis in traumatic brain injury rats

Exercise attenuates neurological deficits by stimulating a critical HSP70/NF-κB/IL-6/synapsin I axis in traumatic brain injury rats

Abstract Background Despite previous evidence for a potent inflammatory response after a traumatic brain injury (TBI), it is unknown whether exercise preconditioning (EP) improves outcomes after a TBI by modulating inflammatory responses. Methods We performed quantitative real-time PCR (qPCR) to qua...

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Bibliographic Details
Main Authors: Chung-Ching Chio, Hung-Jung Lin, Yu-Feng Tian, Yu-Chieh Chen, Mao-Tsun Lin, Cheng-Hsien Lin, Ching-Ping Chang, Chien-Chin Hsu
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Journal of Neuroinflammation
Subjects:
Brain injury
Neuroprotection
Neuroinflammation
Exercise
IL-6
HSP70
Online Access:http://link.springer.com/article/10.1186/s12974-017-0867-9

Internet

http://link.springer.com/article/10.1186/s12974-017-0867-9

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