Sustained delivery of chABC improves functional recovery after a spine injury

Abstract Introduction Chondroitinase ABC (chABC) is an enzyme could improve regeneration and thereby improving functional recovery of spinal cord injury (SCI) in rodent models. Degradation of the active enzyme and diffusion away from the lesion are the causes of using hydrogels as a scaffold to deli...

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Bibliographic Details
Main Authors: Atousa Sharifi, Ali Zandieh, Zahra Behroozi, Michael R. Hamblin, Sara Mayahi, Mahmoud Yousefifard, Fatemeh Ramezani
Format: Article
Language:English
Published: BMC 2022-10-01
Series:BMC Neuroscience
Subjects:
Online Access:https://doi.org/10.1186/s12868-022-00734-8