Effects of malleable kinetochore morphology on measurements of intrakinetochore tension

The distance between fluorescent spots formed by various kinetochore proteins (delta) is commonly interpreted as a manifestation of intrakinetochore tension (IKT) caused by microtubule-mediated forces. However, large-scale changes of the kinetochore architecture (such as its shape or dimensions) may...

Full description

Bibliographic Details
Main Authors: Fioranna Renda, Valentin Magidson, Irina Tikhonenko, Rebecca Fisher, Christopher Miles, Alex Mogilner, Alexey Khodjakov
Format: Article
Language:English
Published: The Royal Society 2020-07-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.200101