Lysosome‐dependent FOXA1 ubiquitination contributes to luminal lineage of advanced prostate cancer

Lysosome‐dependent FOXA1 ubiquitination contributes to luminal lineage of advanced prostate cancer

Changes in FOXA1 (forkhead box protein A1) protein levels are well associated with prostate cancer (PCa) progression. Unfortunately, direct targeting of FOXA1 in progressive PCa remains challenging due to variations in FOXA1 protein levels, increased FOXA1 mutations at different stages of PCa, and e...

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Bibliographic Details
Main Authors: Sherly I. Celada, Guoliang Li, Lindsay J. Celada, Wenfu Lu, Thanigaivelan Kanagasabai, Weiran Feng, Zhen Cao, Nazifa Salsabeel, Ninghui Mao, LaKendria K. Brown, Zaniya A. Mark, Michael G. Izban, Billy R. Ballard, Xinchun Zhou, Samuel E. Adunyah, Robert J. Matusik, Xiaofei Wang, Zhenbang Chen
Format: Article
Language:English
Published: Wiley 2023-10-01
Series:Molecular Oncology
Subjects:
FOXA1
luminal lineage
prostate cancer
SKP2
ubiquitination
Online Access:https://doi.org/10.1002/1878-0261.13497

Internet

https://doi.org/10.1002/1878-0261.13497

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