Expression of NLRP3 inflammasome in leprosy indicates immune evasion of Mycobacterium leprae

Expression of NLRP3 inflammasome in leprosy indicates immune evasion of Mycobacterium leprae

BACKGROUND Leprosy is an infectious-contagious disease caused by Mycobacterium leprae that remain endemic in 105 countries. This neglected disease has a wide range of clinical and histopathological manifestations that are related to the host inflammatory and immune responses. More recently, the inf...

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Bibliographic Details
Main Authors: Ana Luisa Gomes Mendes, Heloísa Di Matteo Joaquim, Mara Inês Stefanini Zamae, Ramon Meira Assis, Jéssica Renata de Moura Peixoto, Margarida Maria Gomes de Araújo, Antônio Carlos Martins Guedes, Edward José Oliveira, Vanessa Peruhype Magalhães, Marcelo Antônio Pascoal-Xavier
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2020-02-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
leprosy
inflammasome
NLRP3
caspase
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762020000100303&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762020000100303&tlng=en

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