Aspirin/PLGA coated 3D-printed Ti-6Al-4V alloy modulate macrophage polarization to enhance osteoblast differentiation and osseointegration

Abstract Although titanium (Ti) and Ti-based alloy have been widely used as dental and orthopedic implant materials, its bioinertness hindered the rapid osseointegration. Therefore, it is recommended to acquire ideal topographic and chemical characteristics through surface modification methods. 3D p...

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Bibliographic Details
Main Authors: Yapeng You, Wanmeng Wang, Ying Li, Yunjia Song, Jian Jiao, Yao Wang, Bo Chen, Jialin Liu, Hui Qi, Yu Liang
Format: Article
Language:English
Published: Springer 2022-10-01
Series:Journal of Materials Science: Materials in Medicine
Online Access:https://doi.org/10.1007/s10856-022-06697-w