Ramelteon Protects Intestinal Tissue Against Injury Caused by Methotrexate Via Showing Anti-apoptotic, Antiinflammatory and Antioxidant Properties

Objective:Methotrexate (MTX), a drug used in the treatment of autoimmune diseases and cancers, is a folic acid antagonist, but it has toxic effects on the gastrointestinal system (GIS). In this study, we examined the anti-inflammatory, antioxidant and anti-apoptotic effects of Ramelteon (RAM), a mel...

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Bibliographic Details
Main Authors: Deniz ÇATAKLI, Mehmet Abdulkadir SEVÜK, Samet COŞAN, Orhan İMECİ, Emine KESKİN, Yavuz Selim SEVİNÇ, Muazzez TIKIRDIK, Melek Yeşim AK, Meltem ÖZGÖÇMEN
Format: Article
Language:English
Published: Galenos Publishing House 2022-12-01
Series:Bezmiâlem Science
Subjects:
Online Access: http://bezmialemscience.org/archives/archive-detail/article-preview/ramelteon-protects-ntestinal-tissue-against-njury-/57570