Sensitization of Resistant Breast Cancer Cells with a Jumonji Family Histone Demethylase Inhibitor

In the present study, we evaluated JIB-04, a small-molecule epigenetic inhibitor initially discovered to inhibit cancer growth, to determine its ability to affect deep intrinsic resistance in a breast cancer model. The model was based on a function-based approach to the selection of cancer cells in...

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Bibliographic Details
Main Authors: Balraj Singh, Vanessa N. Sarli, Anthony Lucci
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/11/2631