Hydroxychloroquine Effects on THP-1 Macrophage Cholesterol Handling: Cell Culture Studies Corresponding to the TARGET Cardiovascular Trial

Hydroxychloroquine Effects on THP-1 Macrophage Cholesterol Handling: Cell Culture Studies Corresponding to the TARGET Cardiovascular Trial

<i>Background and Objectives</i>: Cardiovascular (CV) risk is elevated in rheumatoid arthritis (RA). RA patient plasma causes pro-atherogenic derangements in cholesterol transport leading to macrophage foam cell formation (FCF). The TARGET randomized clinical trial compares CV benefits o...

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Bibliographic Details
Main Authors: Saba Ahmed, Justin Konig, Lora J. Kasselman, Heather A. Renna, Joshua De Leon, Steven E. Carsons, Allison B. Reiss
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Medicina
Subjects:
atherosclerosis
cholesterol
hydoxychloroquine
macrophage
scavenger receptors
Online Access:https://www.mdpi.com/1648-9144/58/9/1287

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https://www.mdpi.com/1648-9144/58/9/1287

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