Synaptic coupling of inner ear sensory cells is controlled by brevican-based extracellular matrix baskets resembling perineuronal nets

Synaptic coupling of inner ear sensory cells is controlled by brevican-based extracellular matrix baskets resembling perineuronal nets

Abstract Background Perineuronal nets (PNNs) are specialized aggregations of extracellular matrix (ECM) molecules surrounding specific neurons in the central nervous system (CNS). PNNs are supposed to control synaptic transmission and are frequently associated with neurons firing at high rates, incl...

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Bibliographic Details
Main Authors: Mandy Sonntag, Maren Blosa, Sophie Schmidt, Katja Reimann, Kerstin Blum, Tobias Eckrich, Gudrun Seeger, Dietmar Hecker, Bernhard Schick, Thomas Arendt, Jutta Engel, Markus Morawski
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Biology
Subjects:
Brevican
Cochlea
Inner hair cell
Ribbon synapse
Extracellular matrix
Perineuronal net
Online Access:http://link.springer.com/article/10.1186/s12915-018-0566-8

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http://link.springer.com/article/10.1186/s12915-018-0566-8

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