Synthesis and Antiviral Activity of N-Phenylbenzamide Derivatives, a Novel Class of Enterovirus 71 Inhibitors

A series of novel N-phenylbenzamide derivatives were synthesized and their anti-EV 71 activities were assayed in vitro. Among the compounds tested, 3-amino-N-(4-bromophenyl)-4-methoxybenzamide (1e) was active against the EV 71 strains tested at low micromolar concentrations, with IC50 values ranging...

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Bibliographic Details
Main Authors: Zhuo-Rong Li, Yu-Huan Li, Jian-Dong Jiang, Yan-Ping Li, Rong-Mei Gao, Wei-Ying He, Lan-Hu Hao, Hui-Qiang Wang, Xing-Yue Ji
Format: Article
Language:English
Published: MDPI AG 2013-03-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/18/3/3630