WTAP-mediated m6A modification of lncRNA NORAD promotes intervertebral disc degeneration

Intervertebral disc degeneration (IVDD) is the leading cause of low back pain and Nucleus pulposus cell senescence contributes a lot to its progression. Here, the authors reveal WTAP-mediated m6A modification of lncRNA NORAD promotes IVDD.

Bibliographic Details
Main Authors: Gaocai Li, Liang Ma, Shujie He, Rongjin Luo, Bingjin Wang, Weifeng Zhang, Yu Song, Zhiwei Liao, Wencan Ke, Qian Xiang, Xiaobo Feng, Xinghuo Wu, Yukun Zhang, Kun Wang, Cao Yang
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-28990-6