The temporal pattern of synaptic activation determines the longevity of structural plasticity at dendritic spines

Summary: Learning is thought to involve physiological and structural changes at individual synapses. Synaptic plasticity has predominantly been studied using regular stimulation patterns, but neuronal activity in the brain normally follows a Poisson distribution. We used two-photon imaging and gluta...

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Bibliographic Details
Main Authors: Ali Özgür Argunsah, Inbal Israely
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223009124