EGFR signaling and pharmacology in oncology revealed with innovative BRET-based biosensors

EGFR signaling and pharmacology in oncology revealed with innovative BRET-based biosensors

Abstract Mutations of receptor tyrosine kinases (RTKs) are associated with the development of many cancers by modifying receptor signaling and contributing to drug resistance in clinical settings. We present enhanced bystander bioluminescence resonance energy transfer-based biosensors providing new...

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Bibliographic Details
Main Authors: Florence Gross, Arturo Mancini, Billy Breton, Hiroyuki Kobayashi, Pedro Henrique Scarpelli Pereira, Christian Le Gouill, Michel Bouvier, Stephan Schann, Xavier Leroy, Laurent Sabbagh
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-05965-5

Internet

https://doi.org/10.1038/s42003-024-05965-5

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