The contact pathway and sepsis

Abstract The contact pathway factors XI (FXI) and XII (FXII) have been demonstrated to be largely dispensable for hemostasis, as their absence results in a mild to absent bleeding diathesis. A growing body of literature, however, suggests that the contact pathway contributes to the pathologic host r...

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Bibliographic Details
Main Authors: Vikram Raghunathan, Jevgenia Zilberman‐Rudenko, Sven R. Olson, Florea Lupu, Owen J. T. McCarty, Joseph J. Shatzel
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Research and Practice in Thrombosis and Haemostasis
Subjects:
Online Access:https://doi.org/10.1002/rth2.12217