Local GHR roles in regulation of mitochondrial function through mitochondrial biogenesis during myoblast differentiation

Local GHR roles in regulation of mitochondrial function through mitochondrial biogenesis during myoblast differentiation

Abstract Background Myoblast differentiation requires metabolic reprogramming driven by increased mitochondrial biogenesis and oxidative phosphorylation. The canonical GH-GHR-IGFs axis in liver exhibits a great complexity in response to somatic growth. However, the underlying mechanism of whether lo...

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Bibliographic Details
Main Authors: Bowen Hu, Changbin Zhao, Xiangchun Pan, Haohui Wei, Guodong Mo, Mingjian Xian, Wen Luo, Qinghua Nie, Hongmei Li, Xiquan Zhang
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Cell Communication and Signaling
Subjects:
GHR
IGF1
Mitochondrial biogenesis
Mitochondrial function
Myoblast differentiation
Online Access:https://doi.org/10.1186/s12964-023-01166-5

Internet

https://doi.org/10.1186/s12964-023-01166-5

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