EphA2 contributes to disruption of the blood-brain barrier in cerebral malaria.

Disruption of blood-brain barrier (BBB) function is a key feature of cerebral malaria. Increased barrier permeability occurs due to disassembly of tight and adherens junctions between endothelial cells, yet the mechanisms governing junction disassembly and vascular permeability during cerebral malar...

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Bibliographic Details
Main Authors: Thayer K Darling, Patrice N Mimche, Christian Bray, Banlanjo Umaru, Lauren M Brady, Colleen Stone, Carole Else Eboumbou Moukoko, Thomas E Lane, Lawrence S Ayong, Tracey J Lamb
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008261