Altered intercellular communication and extracellular matrix signaling as a potential disease mechanism in human hypertrophic cardiomyopathy

Altered intercellular communication and extracellular matrix signaling as a potential disease mechanism in human hypertrophic cardiomyopathy

Abstract Hypertrophic cardiomyopathy (HCM) is considered a primary disorder of the sarcomere resulting in unexplained left ventricular hypertrophy but the paradoxical association of nonmyocyte phenotypes such as fibrosis, mitral valve anomalies and microvascular occlusion is unexplained. To understa...

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Bibliographic Details
Main Authors: Amy Larson, Christina J. Codden, Gordon S. Huggins, Hassan Rastegar, Frederick Y. Chen, Barry J. Maron, Ethan J. Rowin, Martin S. Maron, Michael T. Chin
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-08561-x

Internet

https://doi.org/10.1038/s41598-022-08561-x

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