Identification of a novel, MSC-induced macrophage subtype via single-cell sequencing: implications for intervertebral disc degeneration therapy
Intervertebral disc (IVD) degeneration is a common pathological condition associated with low back pain. Recent evidence suggests that mesenchymal signaling cells (MSCs) promote IVD regeneration, but underlying mechanisms remain poorly defined. One postulated mechanism is via modulation of macrophag...
Main Authors: | Jinsha Koroth, Casey Chitwood, Ramya Kumar, Wei-Han Lin, Benjamin T. Reves, Todd Boyce, Theresa M. Reineke, Arin M. Ellingson, Casey P. Johnson, Laura S. Stone, Kimberly C. Chaffin, Narendra K. Simha, Brenda M. Ogle, Elizabeth W. Bradley |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2024-01-01
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Series: | Frontiers in Cell and Developmental Biology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fcell.2023.1286011/full |
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