Chicoric acid advanced PAQR3 ubiquitination to ameliorate ferroptosis in diabetes nephropathy through the relieving of the interaction between PAQR3 and P110α pathway

Chicoric acid advanced PAQR3 ubiquitination to ameliorate ferroptosis in diabetes nephropathy through the relieving of the interaction between PAQR3 and P110α pathway

ABSTRACTPurpose This study aimed to examine the impact of CA on DN and elucidate its underlying molecular mechanisms of inflammation.Methods We fed C57BL/6 mice injected with streptozotocin to induce diabetes. In addition, we stimulated NRK-52E cells with 20 mmol/L d-glucose to mimic the diabetic co...

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Bibliographic Details
Main Authors: Weiwei Zhang, Yong Liu, Jiajun Zhou, Teng Qiu, Haitang Xie, Zhichen Pu
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Clinical and Experimental Hypertension
Subjects:
Cichoric acid
ferroptosis
diabetes nephropathy
PAQR3
ubiquitination
Online Access:https://www.tandfonline.com/doi/10.1080/10641963.2024.2326021

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https://www.tandfonline.com/doi/10.1080/10641963.2024.2326021

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