HuR-mediated nucleocytoplasmic translocation of HOTAIR relieves its inhibition of osteogenic differentiation and promotes bone formation

HuR-mediated nucleocytoplasmic translocation of HOTAIR relieves its inhibition of osteogenic differentiation and promotes bone formation

Abstract Bone marrow mesenchymal stem cell (BMSC) osteogenic differentiation and osteoblast function play critical roles in bone formation, which is a highly regulated process. Long noncoding RNAs (lncRNAs) perform diverse functions in a variety of biological processes, including BMSC osteogenic dif...

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Bibliographic Details
Main Authors: Yuheng Li, Weijia Sun, Jianwei Li, Ruikai Du, Wenjuan Xing, Xinxin Yuan, Guohui Zhong, Dingsheng Zhao, Zizhong Liu, Xiaoyan Jin, Junjie Pan, Youyou Li, Qi Li, Guanghan Kan, Xuan Han, Shukuan Ling, Xiqing Sun, Yingxian Li
Format: Article
Language:English
Published: Nature Publishing Group 2023-10-01
Series:Bone Research
Online Access:https://doi.org/10.1038/s41413-023-00289-2

Internet

https://doi.org/10.1038/s41413-023-00289-2

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