Testicular Busulfan Injection in Mice to Prepare Recipients for Spermatogonial Stem Cell Transplantation Is Safe and Non-Toxic.

Testicular Busulfan Injection in Mice to Prepare Recipients for Spermatogonial Stem Cell Transplantation Is Safe and Non-Toxic.

Current methods of administering busulfan to remove the endogenous germ cells cause hematopoietic toxicity, require special instruments and a narrow transplantation time. We use a direct testicular injection of busulfan method for preparing recipients for SSC transplantation. Male ICR mice (recipien...

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Bibliographic Details
Main Authors: YuSheng Qin, Ling Liu, YaNan He, Chen Wang, MingYuan Liang, XiaoLi Chen, HaiSheng Hao, Tong Qin, XueMing Zhao, Dong Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4752460?pdf=render

Internet

http://europepmc.org/articles/PMC4752460?pdf=render

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