Disruption of adipocyte YAP improves glucose homeostasis in mice and decreases adipose tissue fibrosis

Disruption of adipocyte YAP improves glucose homeostasis in mice and decreases adipose tissue fibrosis

Objective: Adipose tissue is a very dynamic metabolic organ that plays an essential role in regulating whole-body glucose homeostasis. Dysfunctional adipose tissue hypertrophy with obesity is associated with fibrosis and type 2 diabetes. Yes-associated protein 1 (YAP) is a transcription cofactor imp...

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Bibliographic Details
Main Authors: Daniel J. Han, Rukhsana Aslam, Paraish S. Misra, Felix Chiu, Tanvi Ojha, Apu Chowdhury, Carmen K. Chan, Hoon-Ki Sung, Darren A. Yuen, Cynthia T. Luk
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Molecular Metabolism
Subjects:
Yes-associated protein
Adipose tissue
Insulin resistance
Obesity
Diabetes
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877822001636

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http://www.sciencedirect.com/science/article/pii/S2212877822001636

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