Exploring Alkyl Ester Salts of L-Amino Acid Derivatives of Ibuprofen: Physicochemical Characterization and Transdermal Potential

Exploring Alkyl Ester Salts of L-Amino Acid Derivatives of Ibuprofen: Physicochemical Characterization and Transdermal Potential

This research presents novel ibuprofen derivatives in the form of alkyl ester salts of L-amino acids with potential analgesic, anti-inflammatory, and antipyretic properties for potential use in transdermal therapeutic systems. New derivatives of (<i>RS</i>)-2-[4-(2-methylpropyl)phenyl]pr...

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Bibliographic Details
Main Authors: Kordian Witkowski, Anna Nowak, Wiktoria Duchnik, Łukasz Kucharski, Łukasz Struk, Paula Ossowicz-Rupniewska
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Molecules
Subjects:
ibuprofen
transdermal drug delivery system
chemical modification of an active pharmaceutical agent
nonsteroidal anti-inflammatory drug
permeability
bioavailability
Online Access:https://www.mdpi.com/1420-3049/28/22/7523

Internet

https://www.mdpi.com/1420-3049/28/22/7523

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